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Adderall contains a combination of amphetamine salts, which increase the release of neurotransmitters and block their reuptake, enhancing stimulation in areas of the brain responsible for focus and executive function. The 12.5 mg dosage is often part of a titration plan — it sits between lower doses like 5 mg or 10 mg and higher doses like 15 mg or 20 mg, tailored to the patient's therapeutic needs.